The Gut–Brain Reset
6-Day Retreat
November 6 – 11, 2026
Right now, as you read this, a hundred million neurons in your gut are talking to your brain. They shape your mood before you feel it, your cravings before you name them, your sleep before you close your eyes. Most of us go a lifetime without ever listening in.
For six days, on the island where the science of the Mediterranean diet was born, you will. This is not a wellness holiday. It’s a recalibration.
Retreat Price Per Person: 2350 €
*The retreat programme does not include accommodation, allowing you the flexibility to select the room category that best suits your stay.
The Gut–Brain Reset Begins Where Generic Retreats End: with your Biology
Personalised prognostic testing maps the current state of your gut–brain axis — so that everything that follows is designed around your body, not a template. Then, day by day, we rebuild the conversation between your two brains:
Eat — food as signal, not just fuel: Cretan ingredients chosen for what they say to your microbiome, from the soil that first taught the world what longevity tastes like.
Breathe — guided breathwork that speaks directly to your vagus nerve, the body’s own reset switch, shifting you out of stress physiology and into repair.
Move — functional movement designed to restore the rhythms your nervous system evolved to expect.
Rest — sleep practices and restorative treatments that let the night do what six days of insight cannot: consolidate change into biology.
Understand — talks and workshops with our scientific team that turn cutting-edge longevity research into decisions you can actually make on a Tuesday morning back home.
The Gut–Brain Reset Itinerary Includes:
Day 1 — Arrive & Connect
- Arrival & Welcome Wellness Drinks
- Nao Longevity Hub Tour
- Welcome Circle & Journaling
- Prognostic Assessments
- Dinner Buffet - Meet the Community at the Cretan Longevity Table
Day 2 — Nourish & Restore
- Prognostic Assessments (if not completed on Day 1)
- Breakfast
- Hydrotherapy & Treatments
- Lunch - Mediterranean Anti-Inflammatory Table
- Expert Lecture
- Personalised Treatments & Leisure Time
- Dinner
Day 3 — Cultivate Your Inner Ecosystem
- Gut–Brain Morning Flow
- Breakfast
- Cooking & Fermentation Lab — “Cultivating Your Inner Ecosystem” & Lunch
- Personalised Treatments & Leisure
- Guest Chef's Dinner
Day 4 — From Landscape to Table
- Breathe & Ground Yoga
- Breakfast
- Signature Outdoor Experience — Cretan Foraging Journey & Lunch
- Personalised Treatments & Leisure
- Expert Lecture
- Dinner
- Sound Bath Session
Day 5 — Optimise & Integrate
- Brain Gym
- Breakfast
- Coffee & Longevity Workshop
- Lunch
- Personalised Treatments & Leisure
- Expert Lecture
- Mediterranean Social Dinner & Live Music
Day 6 — From Insight to Action
- Breakfast
- Expert Longevity Consultation
- Closing Circle
The Retreat Experience
The retreat is built around the idea that healthy ageing is not about endlessly optimising the body, but about understanding it better.
What you take home?
Not a glow that fades by the second week. You leave with a personal map of your own gut–brain axis, a set of daily rituals engineered to fit your real life, and something rarer: the felt experience of what your body is like when both brains are finally working together. That memory becomes your new baseline — and your reason to protect it.
Six days. One conversation you’ll never stop listening to.
Personalised Prognostics & Gut Health Ιnsights
Morning Flow, Breathwork, Brain Gym & Guided Meditation
Hydrotherapy and Personalised Treatments
Authentic Cretan Outdoor Experiences
Hands-on Fermentation & Cooking Class
Mediterranean Anti-Inflammatory Nutrition
Sleep & Nervous-System Practices
Curated Social Experiences
Full-Board Meals
Personalised Prognostics & Gut Health Ιnsights
Morning Flow, Breathwork, Brain Gym & Guided Meditation
Hydrotherapy and Personalised Treatments
Authentic Cretan Outdoor Experiences
Hands-on Fermentation & Cooking Class
Mediterranean Anti-Inflammatory Nutrition
Sleep & Nervous-System Practices
Curated Social Experiences
Full-Board Meals
All the Nao Treatements Included at the Retreat
Assessments & Wellness Facility
- Microbiome Assessment
- Resting Metabolic Rate Assessment
- Wellbeing Body Composition Scan
- HRV Assessment (Heart Rate Variability)
- Skin Analysis
Technology & Therapies
- Brain Gym Session (60')
- 2 x Cryotherapy Session
- Photobiomodulation Session
- Vibroacoustics Session
- 2 x Neuromodulation Session
- Massage (60')
- Nervous System Reset Treatment(120')
- QMS Facial Therapy (60')
- Hydrotherapy Thermal Circuit
About Minos Palace Resort & Nao Longevity Hub
Minos Palace Resort, a modern-day sanctuary in Crete with 360° sea views, blends innovative wellbeing, bespoke design, and a unique landscape to create a truly transformative journey.
At Nao Longevity Hub, you’ll discover guidance to enhance your longevity journey, leading to a happier and more fulfilling life.
Nao Longevity Hub features thoughtfully designed spaces including 8 treatment rooms, Brain Gym, Cryotherapy, infrared sauna, photobiomodulation and vibroacoustic therapy areas, relaxation and meditation zones, hot and cold plunges, an emotional tunnel, and the vitality pool—each crafted to support a holistic, science-based, and profoundly human wellbeing experience.
How to Get Here
Located in Lasithi, in Eastern Crete, the hotel is easily accessible with a 50-minute drive from Heraklion Airport (HER), a 60-minute drive from Heraklion Port, or a 180-minute drive from Chania Airport (CHQ).
Athens (ATH) connects to Heraklion (HER) with around 11 direct flights per day via Aegean Airlines and Sky Express. From elsewhere in Europe, there are seasonal direct flights to Heraklion from cities such as Frankfurt, Munich, Brussels, Milan, Rome, Zurich, Geneva, London, Manchester, Edinburgh, Paris, Lyon, Nice, and more.
Weather in Eastern Crete in November
In Agios Nikolaos during November, expect mild and pleasant days around 19‑20°C, with evenings cooling to 13‑15°C. The sea remains inviting at 20‑21°C, perfect for refreshing swims. Daylight lasts about 10 to 10½ hours, with sunrises and sunsets that linger, offering truly magical moments of presence and connection with the surroundings.